Application Deadline
July 31, 2021

Scientist ─ Molecular Biology

Our biotech company, MultiplexDX, aims to use the latest advance in molecular biology and the power of genomics to develop novel molecular diagnostic tools for the detection of infectious diseases and cancer.

Through a recently awarded EIC Accelerator grant, we are conducting a large-scale retrospective validation of our molecular diagnostic test for breast cancer called Multiplex8+. This test uses advances in spatial biology to both visualize and sequence a panel of RNA based biomarkers to differentiate subtypes of breast cancer and ultimately provide prognostic information to develop personalized, effective, and life-saving treatment plans.

The position

We are looking for a Scientist with experience in Molecular Biology to join our team in planning, conducting, and optimizing RNA-based diagnostic experiments.

In this multifaceted role, you will help advance our next pipeline of designed diagnostic products, solve technical obstacles, test different concepts in the laboratory, read scientific papers, and generate new ideas in collaboration with our innovative R&D team.

You will report to the Director of Research & Development and Chief Operating Officer and be based at the headquarters in Bratislava, Slovakia. 

Responsibilities

  • Plan, conduct, and optimize RNA-based fluorescent in situ hybridization (FISH) and next-generation sequencing (NGS) experiments
  • Perform molecular biology techniques, including RNA extraction/purification, PCR, qPCR, RNA/small RNA NGS library preparation, RNA quality control (NanoDrop™, Qubit™, Bioanalyzer/Tapestation), gel electrophoresis, etc
  • Use fluorescence microscopy/confocal microscopy and laser capture microdissection to image and dissect RNA-FISH tissue
  • Perform routine histopathological examination of tissues, including tissue processing/preparation (e.g., paraffin-embedding, microtome sectioning) and histological staining (e.g., hematoxylin and eosin staining)  
  • Operate and maintain laboratory & analytical equipment
  • Generate new concepts and ideas in collaboration with the team
  • Document experimental work, analyze data, and present results
  • Prepare written methods and SOPs
  • Present research findings in manuscripts, at conferences, and to potential partners
  • Stay abreast of recent developments in RNA-FISH and RNA NGS and their applications in clinical diagnostics

Requirements

  • Scientist level: Master’s degree or PhD in Molecular Biology (or related field)
  • Practical laboratory experience in one or more of the following techniques is an advantage: RNA-FISH, next-generation sequencing, and molecular biology (PCR)
  • Ability to work independently as well as part of a multidisciplinary team is essential
  • Strong analytical and systematic troubleshooting skills
  • Excellent written and oral communication skills (English is our working language)
  • The ideal candidate should be highly motivated, goal-oriented, and capable of working in a fast-paced environment and meeting project milestones

We offer

We offer a great career with development opportunities in a highly motivating and professional environment. You may be looking for a new career path or simply looking to contribute to a small, hard-working organization with the ambition to make a difference.

You will be offered the opportunity to spearhead the next ground-breaking diagnostic technologies involving RNA-based spatial biology and next-generation sequencing.

The job will be challenging and rewarding at the same time. You will have world class colleagues, 4-5 weeks of paid holiday, and a negotiable salary commensurate to your qualifications (starting from €1500/month, subject to increase after the trial period). Depending on the performance of the company and employee, additional benefits may be granted such as a thirteenth salary and performance bonuses.

Application deadline

Application deadline is July 31st, 2021. Please send the application including your CV or resume and a cover letter to career@multiplexdx.com.

Your application will be treated in accordance with our policies for processing of personal data and the General Data Protection Regulation of the EU.

Background

MultiplexDX’s diagnostic products combine specific, precise, automated, high-throughput, multiplexed and quantitative RNA visualization and sequencing to come up with a specific “barcode” for each cancer, which suggests a unique, personalized treatment strategy. In MultiplexDX’s diagnostic tests, multiplexing stands for cross-validating test results by using two independent perspectives, visualization and sequencing. This multiplexed platform provides the most accurate clinical parameters of a patient’s cancer profile, which enables an oncologist to make an evidence-based decision and target treatment quickly, directly, and more accurately.

For additional information, please contact

Peter Kilian
COO
Ilkovičova 8
84104 Bratislava, Slovakia
career@multiplexdx.com 
www.multiplexdx.com

About MultiplexDX

MultiplexDX is one of the most innovative biotech corporations, created to bring its revolutionary technologies to the market of personalized molecular diagnostics. The company has representation in both U.S. and European markets. The collaborators of MultiplexDX are from the world’s most prestigious scientific organizations including the National Cancer Institute, Rockefeller University, Albert Einstein University, Vanderbilt University, Cornell University, Queens University (Canada), Hebrew University of Jerusalem (Israel), and the Max Delbrück Center for Molecular Medicine (Germany).

MultiplexDX IP-based and innovative platform merges histopathology methods, biomarker quantification, visualization and gene expression with a single-cell resolution by combining MDX proprietary visual and sequencing technologies into one diagnostic test. This cross-validation approach eliminates diagnostic errors and creates 100% precise cancer profiling for each patient which allows clinicians to suggest specific, personalized cancer treatment.

Find out more about MultiplexDX on Corporate website, Facebook, LinkedIn, Twitter