Application Deadline
April 15, 2021

Senior Bioinformatics Scientist

Our biotech company, MultiplexDX, aims to use the latest advance in molecular biology and the power of genomics to develop novel molecular diagnostic tools for the detection of infectious diseases and cancer.

Through a recently awarded EIC Accelerator grant, we are conducting a large-scale retrospective validation of our molecular diagnostic test for breast cancer called Multiplex8+. This test uses advances in spatial biology to both visualize and sequence a panel of RNA based biomarkers to differentiate subtypes of breast cancer and ultimately provide prognostic information to develop personalized, effective, and life-saving treatment plans.

We have also developed a number of nucleic acid tests (both RT-qPCR and LAMP) to detect infectious disease like SARS-CoV-2, influenza, as well as the emerging SARS-CoV-2 variants first discovered in the United Kingdom (lineage B.1.1.7) and South Africa (lineage B.1.351). Our laboratory also participates in routine genomic surveillance efforts to identify and track SARS-CoV-2 variants using Oxford Nanopore sequencing.

Position Summary

We are looking for an experienced Senior bioinformatician to take the lead in designing and analyzing both next generation sequencing (NGS) and third-generation sequencing (e.g., nanopore) experiments.

In this multifaceted role, you will help advance our next pipeline of designed diagnostic products by analyzing large and complex NGS and long-read data sets, developing software tools and algorithms for automated analysis pipelines, solving technical obstacles, producing rich data visualizations and written reports, and generating new ideas in collaboration with our R&D team.

You will report to the Director of Research & Development and Chief Operating Officer and will be based at the headquarters in Bratislava, Slovakia.

Responsibilities

  • Will become part of R&D team to design and analyze NGS and nanopore sequencing experiments.
  • Develop software and bioinformatic tools to advance automated analysis pipelines.
  • Build and maintain computational pipelines on a cloud-based high-performance computing environment.
  • Make data-driven decisions to advance diagnostic pipelines and refine bioinformatic analysis tools
  • Effectively communicate results with internal and external stakeholders using rich data visualizations, oral/written reports, and scientific publications
  • Will build his/her own team

Requirements

  • PhD in Bioinformatics, Computer Science or related field with demonstrable experience in analyzing sequencing data (both NGS and nanopore).
  • MSc degree holders will be considered if they can demonstrate significant experience.
  • Post graduate experience in industry is a plus
  • Experience with Python, R, Unix command line, version control systems (Git), and standard sequencing bioinformatic tools is strongly preferred
  • Knowledge of machine learning algorithms and their application to sequencing data is strongly preferred
  • Proficiency with statistical inference is preferred
  • Experience analyzing SARS-CoV-2 nanopore sequencing data is a plus
  • Comprehension of basic molecular biology as it pertains to human disease, primarily in cancer and/or infectious diseases.
  • Ability to work independently as well as part of a multidisciplinary team is essential.
  • Rigorous analytical and systematic troubleshooting skills.
  • Demonstration of goal-oriented, hands-on, and innovative approach to problem solving.
  • Excellent organizational and reasoning skills are a must.
  • Excellent written and oral communication skills (English is our working language).

Requirements

We offer a great career with development opportunities in a highly motivating and professional environment. You may be looking for a new career path or simply looking to contribute to a small, hard-working organization with the ambition to make a difference.

You will be offered the opportunity to spearhead the next ground-breaking diagnostic technologies involving RNA-based next-generation sequencing.

The job will be challenging and rewarding at the same time. You will have world class colleagues, flexible working hours, 5 weeks of paid holiday, and a negotiable salary commensurate to your qualifications (starting from €3000/month). This position will be funded for at least one year with the possibility of an extension under awarded EIC Accelerator grant.

Application deadline

Application deadline is April 15th, 2021. Please send the application including your CV or resume with the names of 3 references and a cover letter to career@multiplexdx.com.

Your application will be treated in accordance with our policies for processing of personal data and the General Data Protection Regulation of the EU.

For additional information, please contact

Peter Kilian
COO
Ilkovičova 8
84104 Bratislava, Slovakia
career@multiplexdx.com 
www.multiplexdx.com

About MultiplexDX

MultiplexDX is one of the most innovative biotech corporations, created to bring its revolutionary technologies to the market of personalized molecular diagnostics. The company has representation in both U.S. and European markets. The collaborators of MultiplexDX are from the world’s most prestigious scientific organizations including the National Cancer Institute, Rockefeller University, Albert Einstein University, Vanderbilt University, Cornell University, Queens University (Canada), Hebrew University of Jerusalem (Israel), and the Max Delbrück Center for Molecular Medicine (Germany).

MultiplexDX IP-based and innovative platform merges histopathology methods, biomarker quantification, visualization and gene expression with a single-cell resolution by combining MDX proprietary visual and sequencing technologies into one diagnostic test. This cross-validation approach eliminates diagnostic errors and creates 100% precise cancer profiling for each patient which allows clinicians to suggest specific, personalized cancer treatment.

Find out more about MultiplexDX on Corporate website, Facebook, LinkedIn, Twitter