polyT probe 5 nmol
28S rRNA probe 5 nmol
MultiplexDX hybridization buffer 100 ml
MultiplexDX Wash buffer 1 1000 ml
MultiplexDX Wash buffer 2 1000 ml
MultiplexDX Wash buffer 3 1000 ml
Antifade solution with DAPI 10 ml
FISH results in 4 fluorescence microscopy channels (Cy2, Cy3, Cy5 and Cy7)
Compared to current standard RNA FISH protocols our FullRNAlook is simple, fast and highly reliable and reproducible.
Cancer specimens were examined for rRNA (in red) and poly(A) RNA (in green). RNA fluorescence ratios in the samples are very distinct (greenish (poly(A) high) for Patient A, orange (poly(A) low) for Patient B), providing molecular classification better correlating with prognosis. Greenish color indicating higher tumor malignancy corroborates with clinical outcome of Patient A, who went on to develop distant metastasis compared to free-metastatic Patient B. However, both specimens were similar according to H&E and IHC. In the end, Patient A died due to misdiagnosis and mistreatment. Using our technology, the misdiagnosis would be avoided.
The diagnostic kits vDetect and rTest are based on an improved and re-designed Charité Berlin protocol also recommended by the WHO.
We offer custom, high quality synthesis of aptamers, siRNA, miRNA, antagomirs, qPCR probes, oligonucleotide triphosphates etc.
MDX small RNA sequencing products are compatible with Illumina sequencing technology and designed for the simplest, the most economical, the most precise and automated small RNA library preparation, enabling a great elimination of sequencing errors and biases.
MultiplexDX IP-based and innovative platform merges histopathology methods, biomarker quantification, visualization and gene expression with a single-cell resolution by combining our proprietary visual and sequencing technologies into one diagnostic test.
MultiplexDX offers a wide range of bioinformatics services, including genome assembly, gene expression, metagenomics analyses and data visualization.